\documentclass[a4paper]{letter}
\signature{Your Name Here}
\address{Return address line 0 \\ Return Address line 1 \\ etc...}
% Comment the following line to center the Signature
\longindentation=0pt
\begin{document}
\begin{letter}{Recipient address line 0 \\ Recipient Address line 1 \\ etc...}
\opening{Dear Sir or Madam,}
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%%%%%%%%%%%%%%%%
%%% Closings %%%
%%%%%%%%%%%%%%%%
%%% Formal closings
\closing{Thank you,}
%\closing{Regards,}
%\closing{Respectfully,}
%\closing{Cordially,}
%\closing{With gratitude,}
%\closing{Best regards,}
%\closing{In sympathy,}
%%% Informal closings
%\closing{Best,}
%\closing{All the best,}
%\closing{Thanks,}
%\closing{Talk soon,}
%\closing{Best wishes,}
%\closing{Warmly,}
%\closing{Have a good day/evening/weekend,}
%\closing{Many thanks}
\ps % Paragraph skip
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\end{letter}
\end{document}
